Fig. 1

A Mendel-Fisher view of the average effect of an allele and its additive genetic influence on the phenotypic expression of a trait. In principle, the polygenic risk scores concept is an extension of these foundational concepts
A Mendel-Fisher view of the average effect of an allele and its additive genetic influence on the phenotypic expression of a trait. In principle, the polygenic risk scores concept is an extension of these foundational concepts